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Although losartan may be used to prevent kidney problems or treat people who have kidney problemsit may also rarely cause serious kidney problems or make them worseYour doctor will check your kidney function while you are taking losartanTell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine.

Take this medication by mouth as directed by your doctorusually once daily with or without foodThe dosage is based on your medical condition and response to treatment.

Should exposure to losartan have occurred from the second trimester of pregnancyultrasound check of renal function and skull is recommended.

Get emergency medical help if you have signs of an allergic reaction to Cozaarhivesdifficult breathingswelling of your facelipstongueor throat.

Other antihypertensive agents may increase the hypotensive action of losartanConcomitant use with other substances which may induce hypotension as an adverse reactionlike tricyclic antidepressantsantipsychoticsbaclofen and amifostinemay increase the risk of hypotension.

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