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Cardiac and renal problemsPrednisone can increase blood pressurecause water and sodium retentionand increase potassium and calcium excretionTell your doctor if you have a history of heart or kidney disease.

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofcurrent/past infectionssuch as fungal infectionstuberculosisherpesheart problemssuch as heart failurerecent heart attackhigh blood pressurethyroid problemskidney diseaseliver diseasestomach/intestinal problemssuch as ulcerdiverticulitisbone lossosteoporosismental/mood disorderssuch as psychosisanxietydepressioneye diseasessuch as cataractsglaucomadiabetesmineral imbalancesuch as low level of potassium/calcium in the bloodseizuresblood clotsbleeding problems.

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types of drugs known to interact with flonase or fluticasone include drugs used to treat hiv, including ritonavir norvir , saquinavir fortovase, invirase antifungal medications, such as itraconazole sporanox , fluconazole diflucan , and ketoconazole nizoral antidepressants, such as nefazodone serzone , fluoxetine prozac, sarafem , and paroxetine paxil certain antibiotics, including clarithromycin biaxin and metronidazole flagyl oral steroids, such as dexamethasone decadron, dexone , methylprednisolone medrol , and prednisone deltasone some drugs used to treat mental illness, such as fluvoxamine luvox the heartburn drug cimetidine tagamet certain heart medications, such as amiodarone cordarone and verapamil calan, covera, isoptin, verelan hormonal contraceptives, including birth control pills, patches, rings, injections, and implants the asthma drug zafirlukast accolate .