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Another study of 125 patients concluded that panic-like symptoms may explain the chest pain and related side effects after sumatriptan administration in patients with high levels of anxietyRef]

11Product InformationImitrex nasal spraysumatriptanGlaxo WellcomeResearch Triangle ParkNC.

Sumatriptan does not prevent future migraines or lessen how often you get migraine attacks.

One report has suggested thatthroat tightnessand chest pain associated with sumatriptan may sometimes be attributable to changes in esophageal motilityRef]

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in all 3 trials, the percentage of patients achieving headache response 2 and 4 hours after treatment was significantly greater among patients receiving imitrex tablets at all doses compared with those who received placebo.