Information about Olanzapine.

Olanzapine can cause orthostatic hypotensiona drop in blood pressure upon standing up that may cause dizziness or even faintingTaking olanzapine with either diazepamValiumother related benzodiazepines or alcohol can exaggerate the orthostatic hypotension caused by olanzapine.

Irreversibleinvoluntarydyskinetic movements may develop with antipsychotic drugsprevalence appears to be highest among elderly individualsespecially elderly womendiscontinue if clinically appropriate.

NMS is a potentially life-threatening condition associated with antipsychotic medicinal productsRare cases reported as NMS have also been received in association with olanzapineClinical manifestations of NMS are hyperpyrexiamuscle rigidityaltered mental statusand evidence of autonomic instabilityirregular pulse or blood pressuretachycardiadiaphoresisand cardiac dysrhythmiaAdditional signs may include elevated creatine phosphokinasemyoglobinuriarhabdomyolysisand acute renal failureIf a patient develops signs and symptoms indicative of NMSor presents with unexplained high fever without additional clinical manifestations of NMSall antipsychotic medicinesincluding olanzapine must be discontinued.

This document does not contain all possible interactionsThereforebefore using this producttell your doctor or pharmacist of all the products you useKeep a list of all your medications with youand share the list with your doctor and pharmacistCheck with your physician if you have health questions or concerns.

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when using prozac and olanzapine in combination, also refer to the use in specific populations section of the package insert for symbyax.