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If your doctor has directed you to use this medicationyour doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for themDo not startstopor change the dosage of any medicine before checking with your doctorhealth care provider or pharmacist first.

The thiazides may decrease serum PBI levels without signs of thyroid disturbance.

For the treatment of edema associated with congestive heart failurecirrhosis of the liverand the nephrotic syndromealso in steroid-induced edemaidiopathic edemaand edema due to secondary hyperaldosteronism.

Possible exacerbation or activation of systemic lupus erythematosus by thiazides has been reported.

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if the patient becomes hypokalemic on 50 mg of hydrochlorothiazide then you may be transferred directly to the hydrochlorothiazide 50 mg-triamterene 75 mg orally per day.